Dr. R. Rathinam

Chief, Uvea Services
Principal – Postgraduate Institute of Ophthalmology
Active Reg.No
Aravind Eye Hospital, Madurai

Dr. Rathinam is the Chief of Uveitis Service & Principal of PG Institute ophthalmology.  She graduated in medicine from Madurai University, DO and MNAMS (Ophthalmology) from Aravind Eye Hospital Madurai, Ph.D. from Dr. M.G.R. University and FAMS from National Academy of Medical Sciences, New Delhi.

Her basic, epidemiological and clinical research over 30 years at uveitis clinic, Aravind Eye Care System uncovered the cause, source and pathogenesis for three new unknown outbreaks, which include Ocular Leptospirosis, Trematode eye disease in children and Ocular West Nile virus infection . She received the prestigious Prof. C.S Bhaskaran Oration award and P.Siva Reddy International Award for her Research on novel infectious uveitis etiologies from All India Ophthalmology Society (AIOS) 2014 and from Indian Association of Medical Microbiologists (IAMM). She has made outstanding contributions to ophthalmic literature both in national and international arena. She is an elected member of International Uveitis Study Group (IUSG) since 2001.

Total number of publications including Book chapters at present -151

Total citations of these publications received are 2897, h-index-31, i10-index- 59, fifty nine papers have received more than 10 citations. Maximum citation received by the land mark paper on epidemiology is 362. (As on 8/1/2022)

The article, Rathinam SR, Babu M, Thundikandy R, et al A Randomized Clinical Trial Comparing Methotrexate and Mycophenolate Mofetil for Noninfectious Uveitis. Ophthalmology. 2014 was one out of 12 uveitis papers selected by members of the American Uveitis Society for their outstanding teaching value for residents published in 2014

Dr. Rathinam has contributed chapters for books published in India, United Kingdom, Germany and the United States of America, Co Editor for Wills eye manual uvea atlas, USA and authored a manual on Ocular Pharmacology.

Research experience

  • Ph.D., Dissertation by Dr.Rathinam: The TN Dr.MGR University, Chennai

Study on clinical presentation, diagnosis and management of infectious uveitis with reference of leptospirosis

  • Collaborative research with  Royal tropical institute Netherland-2001-2002 

A pilot study to establish the leptospiral etiology of uveitis.

  • Collaborative research with Indian Council of Medical Research- 1997-2001

Value of culture and serology in ophthalmic complication of leptospirosis

Evaluation of PCR and other parameters in diagnosis of tubercular uveitis

  • Collaborative research with Proctor Foundation, San Francisco, USA (1997-1998)

PCR assay of aqueous humor in an epidemic outbreak of leptospirosis in India

Principal investigator – Basic research projects

  1. Etiology and immunopathogenesis of subconjunctival and anterior chamber granulomatous uveitis in children of South India – Funded by ICMR (2011-2014).

Co Investigator – Basic research projects

  1. Standardization and application of Multiplex PCR in the detection of infectious agents in the intraocular fluid of patients with retinochoroiditis –      (ICMR) – 2006-2009
  2. Molecular insights into the etiology of infectious uveitis (DBT) – 2007- 2010
  3. Antigenic mimicry between leptospiral and human lens proteins (ALCON) 2008-2011
  4. Cytokine profile in aqueous humor of Trematode Granuloma (ALCON) 2008-2011

International Drug trials 2006-2012 (Principal investigator)

  1. FAST Study NIH funded : First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Pilot Trial- Proctor Foundation (from 2015-17)
  2. Sakura Study :A Phase III, Multinational, Multicenter, Randomized, Double – Masked, Study Assessing the Safety and Efficacy of Intravitreal Injections of DE-109 (three doses) for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the eye – Santen Pharmaceutical Co., Ltd (2011-2013)
  3. Protocol CAIN457C2301: A 24 week multicenter, randomized, double-masked, placebo controlled, dose-ranging phase III study of AIN 457 versus placebo for maintaining uveitis suppression when reducing systemic  immunosuppression in patients with quiescent, non-infectious intermediate, posterior or panuveitis  (ENDURE study)
  4. Novartis -2010Protocol: CAIN457C2303 : A 24 week multicenter, randomized, double-masked, placebo controlled study to assess the difference in the rate of recurrent exacerbations in Behçet’s patients with posterior or panuveitis treated with AIN457 vs placebo adjunctive to standard-of-care immunosuppressive therapy .
  5. Lux –Bio 2007-2008.Double-Masked, Placebo-Controlled, Multi-Center, Dose Ranging Study with an optional extension to assess the Efficacy and Safety of LX211 as Therapy in Subjects with Active Sight threatening, Non-Infectious Uveitis (01and 03) and Clinically Quiescent Sight Threatening, Non-Infectious Uveitis (02).
  6. Allergan An 8-Week, Multicenter, Masked, Randomized Trial (with an 18-Week Masked Extension) to Assess the Safety and Efficacy of 700µg and 350 µg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System Compared with Sham DEX PS DDS Applicator System in the treatment of Non-Infectious Ocular Inflammation of the Posterior Segment in Patients with Intermediate or Posterior Uveitis –2006

Editorial experience:

  1. Associate editor – For the Journal, Ocular Immunology and Inflammation
  2. Co editor for Uveitis , Wills Eye Color Atlas and Synopsis of Clinic Ophthalmology (Wills Eye Series) Lippincott, USA 2011

Reviewer for following journals

  1. Ocular Immunology and Inflammation (Associate Editor)
  2. The Cochrane Library
  3. American Journal of Ophthalmology
  4. Achieves of Ophthalmology
  5. JAMA
  6. Ocular infection and immunology
  7. Journal of Visualized Experiments.
  8. Journal of postgraduate medicine
  9. Middle East African Journal of Ophthalmology
  10. Indian journal of Ophthalmology
  11. PLOS

List of publications in Peer-Reviewed Journals

  1. Swathi C, Kathirvel K, Lalitha P, Rathinam S R, Devarajan B. Dysregulated expression of microRNAs in aqueous humor from intraocular tuberculosis patients. Mol Biol Rep. 2021 Oct. [Epub].
  2. Radhakrishnan N, Smit D, Venkatesh Prajna N, Rathinam SR. Corneal Involvement in HIV-infected Individuals. Ocul Immunol Inflamm. 2021 Jul 7:1-6. [Epub]
  3. Thundikandy R, Priya CG, Radhakrishnan N, Rathinam SR. In Vivo Confocal Microscopic Evaluation of the Limbus and Cornea in Vogt Koyanagi Haradas Syndrome. Ocul Immunol Inflamm. 2021 Apr 1:1-8. [Epub]
  4. Rathinam SR, Arya LK, Siva Ganesa Karthikeyan R, Sen S. Aqueous humor cytokines and cellular profiles in pediatric ocular granulomas caused by the Trematode Fluke Procerovum sp. Ocul Immunol Inflamm. 2021 Apr 1:1-10. [Epub]
  5. Kelly NK, Chattopadhyay A, Rathinam SR, Gonzales JA, Thundikandy R, Kanakath A, Murugan SB, Vedhanayaki R, Cugley D, Lim LL, Suhler EB, Al-Dhibi HA, Ebert CD, Berlinberg EJ, Porco TC, Acharya NR; FAST Research Group. Health and Vision-Related Quality of Life in a Randomized Controlled Trial Comparing Methotrexate and Mycophenolate Mofetil for Uveitis. Ophthalmology. 2021 Mar 3. [Epub]
  6. Babu K, Biswas J, Agarwal M, Mahendradas P, Bansal R, Rathinam SR, Basu S, Ganesh SK, Konana VK, Vedhanayaki R, Philips M, Choudhary T. Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population – A Multicentre Study. Ocul Immunol Inflamm. 2020 Sep 1:1-5. [Epub] PMID: 32870050
  7. Rathinam SR, Tugal-Tutkun I, Agarwal M, Rajesh V, Egriparmak M, Patnaik G. Immunological tests and their interpretation in uveitis. Indian J Ophthalmol. 2020 Sep;68(9):1737-1748.
  8. Rathinam SR, Chidambaranathan GP. Corneal melt in leptospirosis. Indian J Ophthalmol. 2020 Sep;68(9):1970.
  9. Rathinam SR, Rathakrishnan S. Rapid maturation of unilateral cataract in leptospirosis. Indian J Ophthalmol. 2020 Sep;68(9):1977-1979.
  10. Rathinam SR, Parikh JG, Rao NA. Ocular erythema nodosum leprosum: An immunohistochemical study. Indian J Ophthalmol. 2020 Sep;68(9):2028-2030.
  11. Kong CL, Kelly NK, Sundararajan M, Rathinam SR, et al. Comparison of CD4 Counts with Mycophenolate Mofetil versus Methotrexate from the First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial. Ocul Immunol Inflamm. 2020 Aug 11:1-5. doi: 10.1080/09273948.2020.1774906. Epub ahead of print. PMID: 32779952.
  12. Merrill PT, Clark WL, Banker AS, Fardeau C, Franco P, LeHoang P, Ohno S, Rathinam SR et al; Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Study Group. Efficacy and Safety of Intravitreal Sirolimus for Noninfectious Uveitis of the Posterior Segment: Results from the Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA) Program. Ophthalmology. 2020 Apr 3. [Epub]
  13. Tugal-Tutkun I, Onal S, Stanford M, Akman M, Twisk JWR, Boers M, Oray M, Özdal PÇ, Kadayifcilar S, Amer R, Rathinam SR, Vedhanayaki R, et al The Algorithm for the Diagnosis of Behçet Disease Uveitis in Adults. Ocul Immunol Inflamm. 2020 Apr 14. [Epub]
  14. Agrawal R, Gunasekeran DV,, Rathinam SR, Nguyen QD, Pavesio C, Gupta V et al. The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings. Ocul Immunol Inflamm. 2020 Apr 6. [Epub]
  15. Agrawal R, Testi I, Rathinam SR, R, Zierhut M et al. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 1: Guidelines for Initiating Antitubercular Therapy in Tubercular Ophthalmology. 2020 Jan 11. [Epub]
  16. Parida H, Kannan NB, Rathinam SR. Imaging of Muller cell sheen dystrophy. Indian J Ophthalmol. 2020 Mar;68(3):533-535
  17. Rathinam SR, Thundikandy R, Balagiri K. Knowledge, Attitude, and Practice Towards Leptospirosis among Undergraduate and Postgraduate Medical Students in India. Ocul Immunol Inflamm. 2020 Feb 14:1-6. [Epub]
  18. Rathinam SR, Vedhanayaki R, Balagiri K. A Cross-Sectional Assessment of Knowledge, Attitude, and Practice Toward Leptospirosis among Rural and Urban Population of a South Indian District. Ocul Immunol Inflamm. 2019 Dec 9:1-12. [Epub]
  19. Anjana S, Rekha S, Rathinam SR. Metastatic carcinoma masquerading as lens matter. Indian J Ophthalmol 2019 Dec;;67(12):2046-2047.
  20. Rathinam SR, Irene D, Dharmalingam K, Jeya Maheshwari J. Molecular Mimicry between Betaine Aldehyde Dehydrogenase of Leptospira and Retinal Dehydrogenase 1 of Human Lens: A Potential Trigger for Cataract Formation in Leptospiral Uveitis Patients. Ocul Immunol Inflamm. 2019 Nov;1–8. [Epub]
  21. Rathinam SR, Gonzales J, Radhika T, Anuradha K, Bala Murugan S, Vedhanayaki R,  Lim L, Suhler EB, Al-Dhibi HA, Doan T, Keenan JD, Rao MM, Ebert CD, Nguyen HH, Kim E, Porco TC, Acharya NR; for the FAST Research Group. Effect of Corticosteroid-Sparing Treatment with Mycophenolate Mofetil vs Methotrexate on Inflammation in Patients with Uveitis: A Randomized Clinical Trial. JAMA. 2019;322:936-945.
  22. Kumar JS, Rathinam SR, Karothia D, Parida M. Cloning, expression & evaluation of potential immunogenic recombinant capsid premembrane protein of West Nile virus. Indian J Med Res. 2019;149:656-661.
  23. Nithya V, Rathinam SR, Siva Ganesa Karthikeyan R, Lalitha Prajna. A ten year study of prevalence, antimicrobial susceptibility pattern, and genotypic characterization of Methicillin resistant Staphylococcus aureus causing ocular infections in a tertiary eye care hospital in South India. Infect Genet Evol. 2019;69:203–210.
  24. Cunningham ET Jr, Khairallah M, Rathinam SR, Belfort R Jr, Zierhut M. Mosquito-Borne Uveitis. Ocul Immunol Inflamm. 2018;26:651-653.
  25. Kumar JS, Saxena D, Parida M, Rathinam SR. Evaluation of real-time reverse-transcription loop-mediated isothermal amplification assay for clinical diagnosis of West Nile virus in patients. Indian J Med Res. 2018 Mar;147:293-298.
  26. Rathinam SR, Vijayakumar, B, Gowri Priya, C, Visalakshi, J. Leptospiral Uveitis: usefulness of clinical signs as diagnostic predictors. Ocul Immunol Inflamm. 2018;26:569-576.
  27. Bhagya S, Lalitha, Prajna, Arya LM, Rathinam SR. Polymerase Chian Reaction and its Correlation with Clinical Features and Treatment Response in Tubercular Uveitis. Ocul Immunol Inflamm. 2018;26:845-852.
  28. Rathinam SR. Tubercular Uveitis and Scleritis. Focal Points. 2017:1-15.
  29. Niemeyer KM, Gonzales, J A, Rathinam SR, Manohar Babu, B, Radhika, T, Anuradha, K, Porco, T C, Browne, E N, Rao, M M, Acharya, N R. Quality of Life Outcomes from a Randomized Clinical Trial Comparing Antimetabolites for Intermediate, Posterior, and Panuveitis. Am. J. Ophthalmol. 2017;179:10-17.
  30. Browne EN, Rathinam SR, Anuradha, K, Radhika, T, Manohar Babu, B, Lietman, T M, Acharya, N R. A Bayesian Analysis of a Randomized Clinical Trial Comparing Antimetabolite Therapies for Non-Infectious Uveitis. Ophthalmic Epidemiol. 2017;24:63-70.
  31. Nguyen, Q D Merrill, P T, Clark, W L, Banker, A S, Fardeau, C, Franco, P, LeHoang, P, Ohno, S, Rathinam SR, Thurau, S, Abraham, A, Wilson, L, Yang, Y, Shams, N, Sirolimus Study Assessing Double-Masked Uveitis Treatment. Intravitreal Sirolimus for Noninfectious Uveitis: A Phase III Sirolimus Study Assessing Double-Masked Uveitis Treatment (SAKURA). Ophthalmology. 2016;123:2413-2423.
  32. Shen E, Rathinam SR, Manohar Babu, B, Anuradha, K, Radhika, T, Lee, S M, Browne, E N, Porco, T C, Acharya, N R. Outcomes of Vogt-Koyanagi-Harada Disease: a subanalysis from a randomized clinical trial of antimetabolite therapies. Am. J. Ophthalmol. 2016;168:279-286.
  33. Arya LM, Rathinam SR, Lalitha, Prajna, Usha, Kim R, Sudeep, Ghatani, Tandon, Veena. Trematode Fluke Procerovum Varium as cause of Ocular Inflammation in Children, South India. Emerg Infect Dis. 2016;22:192-200.
  34. Rathinam SR, Rao NA. Anterior Segment Ischemia in Viper Bite. Ocul Immunol Inflamm. 2016;24:49-54.
  35. Lou SM, Montgomery, P A, Larkin, K L, Winthrop, K, Zierhut, M, Rosenbaum, J T, Rathinam SR, Uveitis Specialists Study Group. Diagnosis and Treatment for Ocular Tuberculosis among Uveitis Specialists: the international perspectie. Ocul Immunol Inflamm. 2015;23:32-39.
  36. Cunningham, Emmett T, Rathinam SR, Albini, T A, Chee, S-P, Zierhut, M. Tuberculous Uveitis. Ocul Immunol Inflamm. 2015;23:2-6.
  37. Cunningham Jr., Emmett T, Rathinam SR, Tugal-Tutkun, I, Muccioli, C, Zierhut, M. Vogt Koyanagi-Harada Disease. Ocul Immunol Inflamm. 2014;22:249-252
  38. Rathinam SR Manohar Babu, B, Radhika, T, Kanakath, A, Nardone, N, Esterberg, E, Lee, S M, Enanoria, W T, Porco, T C, Browne, E N, Weinrib, R, Acharya, N R. A Randomized Clinical Trial Comparing Methotrexate and Mycophenolate Mofetil for Noninfectious Uveitis. Ophthalmology. 2014;121:1863-70.
  39. Hornbeak DM, Payal, A, Pistilli, M, Biswas, J, Ganesh, S K, Gupta, V, Rathinam SR, Davis, J L, Kempen, J H. Interobserver Agreement in Clinical Grading of Vitreous Haze using Alternative Grading Scales. Ophthalmology. 2014;121:1643-1648.
  40. Umesh CB, Rathinam SR, Lalitha, Prajna, Niraj Agrawal, Renu, P Rajan. Epiretinal Deposits Post Cataract Extraction. Ret Case Brief Rep. 2013;7:359-361.
  41. Saxena D, Kumar, J S, Parida, M, Rathinam SR, Patro, I K. Development and Evaluation of NS1 Specific Monoclonal Antibody Based Antigen Capture ELISA and its Implications in Clinical Diagnosis of West Nile Virus Infection. J Clin Virol. 2013;58:528-534.
  42. Rathinam SR, Lalitha, Prajna, Arya LM, Praveen Muraly, Shukla, Jyoti, Saxena, Divyasha, Parida, Manmohan. Molecular Diagnosis and Ocular Imaging of West Nile Virus Retinitis and Neuroretinitis. Ophthalmology. 2013;120:1820-1826.
  43. Kamath YS, Rathinam SR, Ankush Kawali. Ocular Toxoplasmis Associated with Scleritis. Indian J Ophthalmol. 2013;61:295-297.
  44. Rathinam SR, Manohar Babu, B. Algorithmic Approach in the Diagnosis of Uveitis. Indian J Ophthalmol. 2013;61:255-262.
  45. Arun Kannan , Gowri Priya, C, Lalitha, Prajna, Rathinam SR. Efficiency of Two Commercial Kits in Serodiagnosis of Leptospiral Uveitis. Indian J Med Microbiol. 2012;30:418-422.
  46. Rathinam SR, Arya LM, Usha, Kim R, Lalitha, Prajna, Veena Tandon. Novel Etiological Agent: molecular evidence for trematode-induced anterior uveitis in children. Arch Ophthal. 2012;130:1481-1483.
  47. Subha S, Rathinam SR, Gowri Priya, C, Manjula Sritharan. Serological Diagnosis of Leptospiral Uveitis by HbpA-IgG ELISA. J Med Microbiol. 2012;61:1681-7.
  48. Davis EJ, Rathinam SR, Okada, A A, Tow, S L, Petrushkin, H, Graham, E M, Chee, S P, Guex-Crosier, Y, Jakob, E, Tugal-Tutkun, I, Cunningham, Emmett Jr., Leavitt, J A, Mansour, A M, Winthrop, K L, Hills, W L, Smith, J R. Clinical Spectrum of Tuberculous Optic Neuropathy. J Ophthalmic Inflamm Infect. 2012;2:183-9.
  49. Batmanabane V, Rathinam SR. Steroids in Leptospiral Uveitis: does the route of administration matter. J Pharmacol Pharmacother. 2012;3:58-60.
  50. Vaishnavi B, Gowri Priya, C and Rathinam SR. Spectrum of Leptospira Species Identified in Patients with Leptospiral Uveitis in an Ophthalmological Institute in South India. Indian J Med Microbiol. 2011;29:444-445.
  51. Shukla J, Saxena, D, Rathinam SR, Lalitha, Prajna, Joseph, C R, Sharma, S, Soni, M, Rao, P V, Parida, M. Molecular Detection and Characterization of West Nile Virus Associated with Multifocal Retinitis in Patients from Southern India. Int J Infect Dis. 2012;16:e53-9.
  52. Rathinam SR, Radha Annamala, Biswas, Jyotirmay. Intraocular Parasitic Infections. Ocul Immunol Inflamm. 2011;19:327-336.
  53. Wender JD, Rathinam SR, Shaw, Richard E, Cunningham, Jr., Emmett T. Intraocular Cysticercosis: case series and comprehensive review of the literature. Ocul Immunol Inflamm. 2011;19:240-245.
  54. Mohideen Abdul Kader, Ramakrishnan, R, Chandrashekaran, Rathinam SR. Granulomatous Anterior Uveitis and Follicular Conjunctivitis Due to Brimonidine Tartrate. Asian J Ophthalmol. 2010;11:50-52.
  55. Rathinam SR, Cunningham Jr., Emmett T. Spontaneous Hyphaema and Acute Ocular Hypertension Associated with Severe Lens-Induced Uveitis. Eye. 2010;24:1822-1824.
  56. Rathinam SR, Krishnadas, R, Ramakrishnan, R, Thulasiraj, RD, Tielsch, J M, Katz, J, Robin, A L, Kempen, J H, Aravind Comprehensive Eye Survey Research Group. Population-Based Prevalence of Uveitis in Southern India. Br J Ophthalmol. 2011;95:463-7.
  57. Rathinam SR, Ashok, KA. Ocular Manifestations of Systemic Disease: ocular parasitosis. Curr Opin Ophthalmol. 2010;21:478-484.
  58. Rathinam SR, Cunningham Jr., Emmett T. Vitiligo Iridis in Patients with a History of Smallpox Infection. Eye. 2010;24:1621-1631.
  59. Martin TD, Rathinam SR, Cunningham Jr., Emmett T. Prevalence, Clinical Characteristics, and caouses of Vision Loss in Children with Vogt-Koyanagi-Harada Disease in South India. Retina. 2010;30:1113-1121.
  60. Tiercy J-M, Rathinam SR, Gex-Fabry, Marianne, Baglivo, Edoardo. A Shared HLA-DRB1 Epitope in the DR Beta First Domain is Associated with Vogt-Koyanagi-Harada Syndrome in Indian Patients. Mol. Vis. 2010;16:353-358.
  61. Cunningham Jr., Emmett T, London NJS, Rathinam SR. Uveitis: a global view. Expert Rev. Ophthalmol. 2010;5:113-114.
  62. Rathinam SR. Treating Uveitis in the Developing World Setting. Int Ophthalmol Clin. 2010;50:219-228.
  63. London NJS. Shukla, Dhananjay, Heiden, David, Rathinam SR, Arevalo, J Fernando, Cunningham Jr., Emmett T. HIV, AIDS in the Developing World. Int Ophthalmol Clin. 2010;50:201-218.
  64. Shukla Dhananjay, Rathinam SR, Cunningham Jr., Emmett T. Leptospiral Uveitis in the Developing World. Int Ophthalmol Clin. 2010;50:113-124.
  65. Rathinam SR. Leprosy Uveitis in the Developing World. Int Ophthalmol Clin. 2010;50:99-111.
  66. London NJ S, Rathinam SR, Cunningham Jr., Emmett T. The Epidemiology of Uveitis in Developing Countries. Int Ophthalmol Clin. 2010;50:1-17.
  67. Manohar Babu B, Rathinam SR. Intermediate Uveitis. Indian J Ophthalmol. 2010;58:21-27.
  68. Jayakumar D, Kavitha, Sivakumar, Rathinam SR, Vasanthi, Gnanam. Geomapping of Trematode-Induced Granulomatous Anterior Uveitis – a Newly Identified cause of Blindness among Children in the Pudukkottai District of the Tamil Nadu State, India. Geospatial Health.2009;4:55-63.
  69. Khairallah M, Chee, S P, Rathinam SR, Attia, S, Venu Nadella. Novel Infectious Agents causing Uveitis. Int Ophthalmol. 2010;30:465-83.
  70. Roe RH, Rathinam SR, Wong, R W, McDonald, H R, Jumper, JM, Cunningham J., E T. Delayed Fellow Eye Involvement in Patients with Vogt-Koyanagi-Harada Disease. Br J Ophthalmol. 2009;93:701-702.
  71. Kempen JH, Ganesh, Sudha K, Sangwan, Virender S, Rathinam SR. Interobserver Agreement in Grading Activity and Site of Inflammation in Eyes of Patients with Uveitis. Am. J. Ophthalmol. 2008;146:813-818.
  72. Gowri Priya C, Rathinam SR, Muthukkaruppan, V R. Evidences for Endotoxin as a Causative Factor for Leptospiral Uveitis in Human. Invest. Ophthalmol. Vis. Sc. 2008;49:5419-24.
  73. Ashutosh Verma, Rathinam SR, Gowri Priya, C, Muthukkaruppan, V R, Stevenson, Brian, Timoney, John F T. LruA and LruB Antibodies in Sera of Humans with Leptospiral Uveitis. Clin Vaccine Immunol. 2008;15:1017-1023.
  74. Rathinam SR, Hadi, M Khazaei. Histopathological Study of Ocular Erythema Nodosum Leprosum and Post-Therapeutic Scleral Perforation: a case Report. Indian J Ophthalmol. 2008;56:417-419.
  75. Arvind V, Rathinam SR. A Pre- And Post-Treatment Evaluation Of Vision-Related Quality Of Life In Uveitis . Indian J Ophthalmol. 2008;56:307-312.
  76. Gowri Priya C, Hoogendijk, K T, Berg, M V D, Rathinam SR, Ahmed, A, Muthukkaruppan, V R, Hartskeeri, R A. Field Rats form a major infection Source of Leptospirosis in and around Madurai. India. J Postgrad Med. 2007;53:236-240.
  77. Carolyn TB, Talbot, Elizabeth A, Rathinam SR, Stevens, Rosaling, Zegans, Micheal E. Diagnosis of Ocular Tuberculosis: a role for New Testing Modalites?. Int Ophthalmol Clin. 2007;47:45-62.
  78. Shukla Dhananjay, Rathinam SR, Cunningham, Emmett T. Contribution of HIV/AIDS to Global Blindness. Int Ophthalmol Clin. 2007;2007:27-43.
  79. Lalitha Prajna, Rathinam SR, Banushree, R, Mahesh Kumar, Vijayakumar, R, Sathe, P. Ocular Involvement Associated with an Epidemic Outbreak of Chikungunya Virus Infection. Am. J. Ophthalmol. 2007;144:552-556.
  80. Rathinam SR, Lalitha, Prajna. Paradoxical Worsening of Ocular Tuberculosis in HIV Patients after Antiretroviral Therapy. Eye. 2007;21:667-668.
  81. Rathinam SR, Namperumalsamy, P. Global Variations and Pattern Changes to Epidemiology of Uveitis. Indian J Ophthalmol. 2007;55:173-184.
  82. Rathinam SR, Lalitha, Prajna. Hypopyon in Leprosy Uveitis. J Postgrad Med. 2007;53:46-47.
  83. Rathinam SR, Rao, Narsing A. Sympathetic Ophthalmia following Postoperative Bacterial Endophthalmitis: a clinicopathologic study. Am. J. Ophthalmol. 2006;141:498-507.
  84. Rathinam SR. Customized LogMAR Charts for Mass Vision-Screening. J Postgrad Med. 2005;51:115.
  85. Rathinam SR. Ocular Manifestations of Leptospirosis. J Postgrad Med. 2005;51:189-194.
  86. Lalitha Prajna, Rathinam SR and Srinivasan, M. Ocular Infections Due to Non-Tuberculous Mycobacteria. Indian J Med Microbiol.2004;22:231-237
  87. Rathinam SR, Rao, N A. Tuberculous Intraocular Infection Presenting with Pigmented Hypopyon: a clinicopathological case report. Br J Ophthalmol. 2004;88:721-722.
  88. Gowri Priya C, Bhavani, K, Rathinam SR, Muthukkaruppan, V R. Identification and Evaluation of LPS Antigen for Serodiagnosis of Uveitis Associated with Leptospirosis. J Med Microbiol. 2003;52:667-73.
  89. Rathinam SR. Ocular Leptospirosis. Curr Opin Ophthalmol. 2002;13:381-386.
  90. Rathinam SR, Lalitha, Prajna, Minu, M Mathen, Prajna, N Venkatesh, Srinivasan, M. Endogenous Nocardial Scleral Abscess: a case report. Asia Pacific J. 2002;14:32-34.
  91. Rathinam SR, Usha, Kim R and Rao, Narsing A. Presumed Trematode-induced Granulomatous Anterior Uveitis: a newly recognized cause of intraocular inflammation in children from South India. Am. J. Ophthalmol. 2002;133:773-779.
  92. Rathinam SR. Ocular Complications of Leptospirosis. Eye Care. 2001;:29-32.
  93. Rathinam SR, Fritche, Thomas R, Srinivasan, M, Vijayalakshmi, P, Read, Russel W, Gautom, Romesh, Namperumalsamy, P, Rao, Narsing A. An Outbreak of Trematode-induced Granulomas of the Conjunctiva. Ophthalmology. 2001;108:1223-1229.
  94. Cunningham, Emmett T, Rathinam SR. TB or not TB: the perennial question. Br J Ophthalmol. 2001;85:127-128.
  95. Rathinam SR, Namperumalsamy, P, Cunningham Jr., Emmett T. Spontaneous Cataract Absorption in Patients with Leptospiral Uveitis. Br J Ophthalmol. 2000;84:1135-1141.
  96. Rathinam SR, Cunningham, Emmett T. Infectious Causes of Uveitis in the Developing World. Int Ophthalmol Clin. 2000;40:137-152.
  97. Rathinam SR, Namperumalsamy, P. Leptospirosis. Ocul Immunol Inflamm. 1999;7:109-118.
  98. Rathinam SR, Namperumalsamy, P, Nozik, Robert A, Cunningham Jr., Emmett T. Vogt-Koyanagi-Harada Syndrome after Cutaneous Injury. Ophthalmology. 1999;106:635-638.
  99. Chu KM, Rathinam SR, Namperumalsamy, P, Dean, Deborah. Identification of Leptospira Species in the Pathogenesis of Uveitis and Determination of Clinical Ocular Characteristics in South India. J Infect Dis. 1998;177:1314-1321.
  100. Rathinam SR, Vijayalakshmi, P, Namperumalsamy, P, Nozik, Robert A, Cunningham Jr., Emmett T. Vogt-Koyanagi-Harada Syndrome in Children. Ocul Immunol Inflamm. 1998;6:155-161.
  101. Rathinam SR, Namperumalsamy, P, Nozik, Robert A, Cunningham Jr., Emmett T. Angle Closure Glaucoma as a Presenting Sign of Vogt-Koyanagi-Harada Syndrome. Br J Ophthalmol. 1997;81:608-609.
  102. Rathinam SR, Selvaraj, S, Dean, D, Nozik, R A, Namperumalsamy, P. Uveitis associated with an epidemic outbreak of leptospirosis. Am. J. Ophthalmol. 1997;124:71-79.
  103. Rathinam SR, Ratnam, S, Sureshbabu, L, Natarajaseenivasan, K. Leptospiral Antibodies in Patients with Recurrent Ophthalmic Involvement. Indian J Med Res. 1996;103:66-68.

List of publications in Non-Peer Reviewed Journals

  1. Rathinam SR. Leptospirosis. TNOA. 1997;36:1-5.
  2. Gowri Priya C, Rathinam SR, Dharmalingam K, Namperumalsamy P. Anterior Chamber Granuloma in Adult Male – A Case Report. TNOA. 1999;40:49-54.
  3. Anand Rajendran, Rathinam SR. Bilateral Acute Retinal Becrosis with Retinal Detachment – A Case Report. TNOA. 1999;40:57-60.
  4. Rathinam SR. Uveitis. TNOA. 1995;33:1-23.
  5. Rathinam SR. Subretinal Fibrosis as a Complication of Vogt-Koyanagi-Harada Syndrome. Karnataka J Ophthalmol. 2005;22:29-31.
  6. Rathinam SR. Investigations in Uveitis. TNOA. 2008;46:15-19.
  7. Rathinam SR. Chikungunya. CHAKSHU. 2008.
  8. Rathinam SR, Kawali Ankush Ashok, Radhika T. Parasitic Infections. TNOA. 2010;48:75-80.
  9. Lalitha, Prajna Lalan Kumar Arya; Geetha, Monoharan; Rathinam, Sivakumar R.Microbiology and Molecular Techniques in the Diagnosis in Infectious Diseasesof the Eye.TNOA.2012;50:121-127.
  10. Prajakta Muley, Anuradha, Rathinam SR. Steroids – A Double Edged Sword. TNOA. 2013;51:67-72.
  11. Rathinam SR, Vidyarani M, Vedhanayaki R. Molecular Diagnostics in Uveitis. TNOA. 2013;53:61-65.
  12. Ankush Kawali, Ahuja Ashish, Rathinam SR. Scleritis in Takayasu Disease. TNOA. 2014;55:106-109.
  13. Rathinam SR. Eminent Ophthalmologist’s Journey. TNOA. 2014;52:178
  14. Anand Rajendran, Pushpanjali R, Rathinam SR. Enhanced Depth Optical Coherence Tomography Imaging – A Review. Delhi J Ophthalmol. 2014;24:181-187.
  15. Rathinam SR, Saurabh A. Uveitis and Leptospirosis. Kerala J Ophthalmol. 2014;26:22-25.
  16. Geetha VKP, Rathinam SR. Functional Vision: what else do we need to do. Kerala J Ophthalmol. 2014;26:182-186.
  17. Vedhanayaki R, Rathinam SR. Trematode granuloma in children. Journal of Ophthalmology and Related Sciences 2020;4(1):1-5.
  18. Mishra C, Upadhyay A, Thundikandy R, Rajesh V, Baliga G, Rathinam S. Tubercular retinal vasculitis in a patient with benign familial fleck retina mimicking frosted branch angiitis. Indian J Ophthalmol Case Rep. 2021 Oct-Dec;1(4):680-682.

Book Chapters

  1.  Rathinam SR. Amyloidosis. In: Sandhu H, Kaplan HJ, editors. Clinical cases in uveitis: differential diagnosis and management. Philadelphia: Elsevier; 2021. p. 94-97.
  2. Rathinam SR. Cysticercosis. In: Sandhu H, Kaplan HJ, editors. Clinical cases in uveitis: differential diagnosis and management. Philadelphia: Elsevier; 2021. p. 262-265.
  3. Rathinam SR. Leptospirosis. In: Sandhu H, Kaplan HJ, editors. Clinical cases in uveitis: differential diagnosis and management. Philadelphia: Elsevier; 2021. p. 266-268.
  4. Rathinam SR. Dengue retinopathy. In: Sandhu H, Kaplan HJ, editors. Clinical cases in uveitis: differential diagnosis and management. Philadelphia: Elsevier; 2021. p. 299-303.
  5. Rathinam S.R. (2020) Ocular Tuberculosis. In: Albert D., Miller J., Azar D., Young L. (eds) Albert and Jakobiec’s Principles and Practice of Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-319-90495-5_15-1
  6. Rathinam SR, Lalitha P. Evaluation of Ocular Tuberculosis. In: Yu H, editor. Inflammatory and Infectious Ocular Disorders. Retina Atlas. Singapore: Springer; 2020. p. 137-141.
  7. Rathinam SR, Vedhanayaki R, Anjana S. Leptospirosis. In: Yu H, editor. Inflammatory and Infectious Ocular Disorders. Retina Atlas. Singapore: Springer; 2020. p. 159-162.
  8. Bhagya S, Rathinam SR. Posterior segment manifestations of leptospirosis. In: Gupta V, Nguyen QD, LeHoang P, Agarwal A, editors. The uveitis atlas. New Delhi: Springer; 2020. p. 335-337.
  9. Manoj RT, Rathinam SR. Hansen’s uveitis. In: Gupta V, Nguyen QD, LeHoang P, Agarwal A, editors. The uveitis atlas. New Delhi: Springer; 2020. p. 201-203.
  10. Vedhanayaki R, Rathinam SR. River water granuloma. In: Gupta V, Nguyen QD, LeHoang P, Agarwal A, editors. The uveitis atlas. New Delhi: Springer; 2020. p. 345-346.
  11. Radhika TM, Rathinam SR. Anterior segment manifestations of Leprosy. In: Gupta V, Nguyen QD, LeHoang P, Agarwal A, editors. The uveitis atlas. New Delhi: Springer; 2020. (In Production)
  12. Rathinam SR. Uveitis nomenclature, classification and clinical work-up in uveitis. In: Prajna NV, editor. Peyman’s principles & practice of ophthalmology. 2nd ed. New Delhi: Jaypee Brothers Medical Publishers; 2019. p. 1353-1367.
  13. Rathinam N A Rao Sympathetic uveitis In Yanoff & Duker, Ophthalmology Elsevier London 2017 In press
  14. Rathinam P. Lalitha Tuberculous Uveitis and Scleritis Focal Points: Clinical Modules for Ophthalmologists. Module In press, 2017
  15. SR Rathinam, Y Kamath Ocular Parasitic Infections In Uveitis: An Update, Springer Publications London 119-132;2016
  16. Sudheer Bhagya,Rathinam SR Posterior Segment Manifestations of Leptospirosis’ in The Uveitis Atlas. Springer Publications London ;2017
  17. Rathinam SR Namperumalsamy P Mycobacterial Infection In: Ryan Stephen Retina 6th Edition Wilkinson, Hinton, Sadda, Wiedemann 2015 Elsevier Canada
  18. Rathinam SR Leptospiral Uveitis In Intraocular Inflammation a. Zierhut M, Ohno S, Orefice F, Pavesio C, Rao N Springer Publisher Germany 2015  in press
  19. Rathinam SR Leptospirosis In Emerging bacterial infections Springer Publications- In press
  20. Rathinam , Prachi Agashe. Uveitis In PG Text Book of Paediatrics, by Piyush Gupta Common Eye Abnormalities, Section 47.5 Jaypee Brothers  New Delhi 2015
  21. Rathinam SR. Uveitic Glaucoma. In Ramakrishnan R editors, Diagnosis and Management of Glaucoma. New Delhi: Jaypee Brothers,2012
  22. Vaishnavi B SR Rathinam Leptospiral uveitis Eye in Systemic Disorders 2012
  23. Rathinam SR; Uveitis made simple :Educational manual : editor, (AIOS)  All IndiaOphthalmological Society , National association of ophthalmologists in India. 2010
  24. Rathinam SR; Applied Anatomy of uveitis in Imaging In Eds A. Gupta, V. Gupta, CP Herbort Uveitis Text and Imaging  2009 Page3-13 JAYPEE Brothers India
  25. Rathinam SR; “Leptospiral Uveitis. In Eds A. Gupta, V. Gupta, CP Herbort Uveitis Text and Imaging  2009 Page 335-347 JAYPEE Brothers India
  26. Rathinam SR; “Anterior granulomatous uveitis, In Eds A. Gupta, V. Gupta, CP Herbort Uveitis Text and Imaging  2009 Page 605-610 JAYPEE Brothers India
  27. Rathinam SR; “Cunningham ET. Leptospirosis. Ed: Cecilia Murphy Current    Ocular therapy  Elsevier Ltd, London 2005
  28. Rathinam SR; Namperumalswamy.P Inflammatory and Infectious Disorders of Uvea in Clinical practice in Ophthalmology. Eds  Sandeep Saxena 2003, Chapter 9, 257-285
  29. Rathinam SR; Basic Concepts on immunology and immunological disorders of the eye. Ed.  Gupta, A K; Krishna, V, Current Topics in Ophthalmology – Vol. 6, New Delhi: B I Churchill Livingstone, 2003
  30. Rathinam SR; Authored a manual on “Ocular Pharmacology” published by Aravind Publication -1991

Membership of Professional Bodies

  1. Elected as a member of International Uveitis study group (IUSG)
  2. Life member of International Society for Leptospirosis (ILS)
  3. Past president of Uveitis Society of India (USI)
  4. Life member of Indian Society for Leptospirosis(ISL)
  5. Member of National Academy of Medical Sciences (NAMS)
  6. Life member of All India Ophthalmological Society (AIOS)
  7. Life member of Tamilnadu Ophthalmic Association (TNOA)
  8. Life member of Indian Medical Association (IMA)
  9. Aravind institutional review board as member, chairman, member secretary since 1998-2011

Conferences conducted:

  • Conducted Uvea 360 conference on 25 years completion of uveitis services- 28& 29th January 2017
  • Course Chairman and Lead Faculty – Annual Research Methodology work shop for Post Graduate students at Aravind eye hospital. Since 2008 till date.
  • Conducted Uveitis update – Pre-conference session – TNOA 1994 – Aravind Eye Hospital, Madurai.
  • Conducted Course on Basics on Uveitis & Neuro-Ophthalmology January, 20-21st, 1996 at Aravind Eye Hospital, Madurai.
  • Conducted III Symposium on Uveitis on I & II February 1998 at Aravind Eye Hospital, Madurai.
  • Conducted Symposium on Leptospirosis on 16th November 1998 at Aravind Eye Hospital, Madurai.
  • Conducted “All India Uveitis Conference” on 12 & 13th January 2000 at Aravind Eye Hospital.
  • Conducted “Sixth All India Uveitis Conference” 2006 at Aravind Eye Hospital.
  • Served as scientific committee chair/Member
    • The 11th IOIS congress and international assembly of ocular inflammation – scientific committee Member
    • Tamil Nadu Ophthalmic Association meet 2015, Madurai- scientific committee chair
    • IOIS 2017 in Lausanne – scientific committee Member

Dr. Rathinam involved in several National and International Research Studies.

  1. Division of Virology, Defense Research and Development Establishment, (DRDE) Gwalior,
    • Molecular diagnosis of West Nile virus infection in Human
  2. Proctor Foundation, San Francisco, USA on:-1997-1998
    • PCR assay of aqueous humor in an epidemic outbreak of leptospirosis in India
  3. Indian Council of Medical Research- 1997-2017
    • Evaluation of PCR and other parameters in diagnosis of tubercular uveitis (1997-98)
    • Value of culture and serology in ophthalmic complication of leptospirosis (2000-2001)
    • Etiology and immunopathogenesis of subconjunctival and anterior chamber granulomatous uveitis in children of South India – Funded by ICMR (2011-2014).
    • Kap Studies On Risk Factors Of Ocular Leptospirosis In South India,(2015-17)
  4. Royal tropical institute Netherland-2001-2002
    • A pilot study to establish the leptospiral etiology of uveitis.
  5. Central university of Hyderabad-
    • Study on nature of leptospiral antigen -2009
  6. International Drug trials 2006-2012 (Principal investigator)
  7. University of Shillong
    • Molecular diagnostics in trematode eye disease in children
  1. 2020: Based on citation, recognized as one of top 2% scientists globally by Stanford university
  2. 2020: Unsung Hero of the American Academy of Ophthalmology
  3. 2018: Prof G. Venkadasamy Endownment Award by Uveitis Society of India
  4. 2018: American Academy Achievement award (AAO)
  5. 2017: Prof. C.S Bhaskaran Oration Award, LVP Eye institute, Bhuvaneswar My Journey in Uveitis
  6. 2014: P.Siva Reddy International Award – Research on novel infectious uveitis etiologies. All India Ophthalmology Society (AIOS) Awards
  7. Elected to the Fellowship of the National Academy of Medical Sciences.(FAMS)
  8. 2001: R.N.Mathur Award – Outstanding service in the field Medical ophthalmology – work done on Ocular Leptospirosis at “All India Ophthalmological Conference”
  9. 2000 & 2014: Recognised as an International Research Associate by Proctor Foundation, Sanfrancisco
  10. 1997: Recognized as Proctor Associate Fellow by Proctor Foundation, Sanfrancisco.
  11. 1997: Bruce Ostler Award – for her work on Ocular leptospirosis from Proctor Foundation, University of California,Sanfrancisco, USA
  12. Best Scientific poster award – First Indian Report on Epidemic Ocular Leptospirosis
  13. University First Rank in Diploma in Ophthalmology
  14. University First Rank in Surgery (Final MBBS)
  15. University First Rank in Pathology (III Year MBBS)

Academical Career

  • Lecturer & Reader in Ophthalmology Aravind Eye Hospital, Madurai – 1990-1999
  • Prof.of ophthalmology- Since 2000
  • Specialty experience – Started Uveitis clinic at Aravind eye hospital under the guidance of Dr. P Namperumalsamy in January 1993.
  • Teaching experience-32 years
  • Invited Faculty American academy uveitis sub specialty day for past 12 years
  • Visiting Professor LVP eye institute, Bhubaneswar 2017
  • Visiting Professor UCSF, Sanfrancisco 2017
  • Invited Faculty in International Conferences: (33)

 Ph.D., guide recognization:

  • The TN Tamil Nadu Dr. MGR Medical University, Chennai (2010)
  • Madurai Kamaraj University, Madurai (2011)
  • Alagappa University, Karaikudi (2012)

Ph.D., examiner for the following Universities:

  • Hyderabad central University, Hyderabad
  • Bharathidasan University, Trichy
  • The Tamil Nadu Dr. MGR Medical University, Chennai
  • Madurai Kamaraj University, Madurai