Dr. N. Venkatesh Prajna

Qualification
DO, DNB, FRCO
Designation
Chief, Cornea & Refractive Surgery Services
Director, Residency Training, Aravind Eye Care System
Secretary, Finance, Aravind Eye Care System
Location
Aravind Eye Hospital, Madurai

Dr. Prajna graduated in medicine from Madurai Medical College, DO and DNB from Aravind Eye Hospital, Madurai.  He is the chief of the department of medical education and the chief of the Cornea department of Aravind Eye Hospitals. He is also the secretary of the Govel trust which runs the organization. After finishing his postgraduate career, he joined Aravind eye hospital in 1993 as a full time consultant. He has been conferred the fellowship of the Royal College of Ophthalmologists, London and is also a member of the advisory board of the International Council of Ophthalmology. His special interests include ophthalmology residency education and his research interests are mainly in the field of fungal keratitis.

Dr. Prajna has published several research papers in peer reviewed International Journals, State Journals; 3 Publications about Teleophthalmology and has authored 2 book chapters so far. He has participated in various National and International meetings in Ophthalmology.

Publications in Peer-Reviewed Journals

  1. Prajna NV, Raheem Rahamathulla. Changing Trends in the Intraocular Lens Acceptance in Rural Tamil Nadu. Indian J Ophthalmol. 1995;43:177-179.
  2. Prajna NV, Raheem Rahamathullah. Reaching the Unreached – The Aravind Odyssey. Asia Pacific J. 1995;7:28-31.
  3. Sathish, Srinivasan, Prajna NV and Srinivasan, M. Pyogenic Granuloma of Cornea: a case report. Indian J Ophthalmol. 1996;44:39-40.
  4. Prajna NV, Ramakrishnan, R, Krishnadas, R, Manoharan, N. Lens Induced Glaucomas – Visual Results and Risk Factors for Final Visual Acuity. Indian J
    Ophthalmol. 1996;44:149-155.
  5. Natchiar, G, Thulasiraj, R D, Negrel, A D, Bangdiwala, Shrikant, Raheem Rahamathullah, Prajna NV, Ellwein, Leon B, Kupfer, Carl. The Madurai Intraocular Lens Study I: a randomized clinical trial comparing complications and vision outcomes of intracapsular cataract extraction and ECCE posterior chamber intraocular lens. Am. J. Ophthalmol. 1998;125:1-13.
  6. Prajna NV, Chandrakanth, K S, Kim, R, Narendran, V, Selvakumar, Selvi, Rohini, G, Manoharan, N, Bangdiwala, Shrikant I, Ellwein, Leon B, Kupfer, Carl. The Madurai Intraocular Lens Study II: clinical outcomes. Am. J. Ophthalmol. 1998;125:14-25.
  7. Prajna NV, Sathish, S, Rajalakshmi, P Chitra, Celine George. Microbiological Profile of Anterior Chamber Aspirates following Uncomplicated Cataract Surgery. Indian J Ophthalmol. 1998;46:229-232.
  8. Prajna NV, Anitha, M, Divya, R, Celine George, Srinivasan, M. Effect of Topical 0.02 Percentage Polyhexamethylene Biguanide on Nocardial Keratitis Associated with Scleritis. Indian J Ophthalmol. 1998;46:251-252
  9. Prajna NV, Manju Pillai, R, Manimegalai, T K, Srinivasan, M. Use of Traditional Eye Medicines by Corneal Ulcer Patients Presenting to a Hospital in South India. Indian J Ophthalmol. 1999;47:15-18.
  10. Sathish, Srinivasan, Arup Chakrabarti and Prajna NV. Traumatic Subconjunctival Dislocation of the Crystalline Lens and its Surgical Management. Ophthalmic Surg lasers Imaging. 1999;30:684-686.
  11. Prajna NV, Venkataswamy, G. Strategies for Correcting Surgical Aphakia. Indian J Ophthalmol. 1999;47:265-266.
  12. Prajna NV, Shanthi, C B, Manimaran, R, Ganesh Babu, B, Selvaraj, S, Natchiar, G. Incidence of Posterior Capsular Opacification following Extracapsular Cataract Surgery with PC-IOL Implantation – Results from Madurai Intraocular Lens Study (MIOLS). Asia Pacific J. 1999;11:20-23.
  13. Prajna NV, Arunava Kundu, Maghizh, A, Srinivasan, M. Primary Acquired Melanosis of Conjunctiva with Corneal Involvement. Asia Pacific J. 1999;11:15-17.
  14. Rajakannan, Gayathri, Prasad, Ramakrishnan, R, Prajna NV. Kearns Sayre Syndrome: an atypical presentation. Indian J Ophthalmol. 2000;48:54-55.
  15. Prajna NV, Ellwein, Leon B, Selvaraj, S, Manjula, K, Kupfer, Carl.The Madurai Intraocular Lens Study IV: posterior capsule opacification. Am. J. Ophthalmol. 2000;130:304-309.
  16. Prajna NV, Manjula, K, Jayachandra Reddy, Ravishankar, Gopinath. A Comparative Study of Suture Materials in Relation to Postoperative Microbial Contamination. Asia Pacific J. 2000;12:9-13.
  17. Prajna NV, Celine George, Selvaraj, S, Lu, Kenneth L, Mcdinnell, Peter J, Srinivasan, M. Bacteriologic and clinical efficacy of ofloxacin 0.3 percentage versus ciprofloxacin 0.3 percentage ophthalmic solutions in the treatment of patients with culture-posive bacterial keratitis. Cornea. 2001;20:175-178.
  18. Minu, M Mathen, Seema Vishnu, Prajna NV, Vijayalakshmi, P, Srinivasan, M. Congenital corneal anesthesia: A series of four case reports. Cornea. 2001;20:194- 196.
  19. Prajna NV, Venkataswamy, G . Cataract Blindness – the Indian Experience. Bull. World Health Organ. 2001;79:259-260.
  20. Prajna NV, Rema Rao, A, Minu, M Mathen, Lalith, Prajna, Celine George, Srinivasan, M.Simultaneous Bilateral Fungal Keratitis caused by Different Fungi. Indian J Ophthalmol.  2002;50:213-214.
  21.  Rathinam, Sivakumar R, Lalitha, Prajna, Minu, M Mathen, Prajna NV, Srinivasan, M. Endogenous Nocardial Scleral Abscess: a case report. Asia Pacific J.2002;14:32-34.
  22. Lolly Patnaik, Prajna NV. Amniotic Membrane Transplantation in Corneal Diseases. Eye Care. 2002:13-17.
  23. Arun Thomas Moreira, Prajna NV. Acanthamoeba as a Cause of Peripheral Ulcerative Keratitis. Cornea. 2003;22:576-577.
  24. Prajna NV, Rajesh Kumar John, Praveen, K Nirmalan, Lalitha, Prajna, Srinivasan, M.A Randomised Clinical Trial Comparing 2 Percentage Econazole and 5 Percentage Natamycin for the Treatment of Fungal Keratitis. Br J Ophthalmol. 2003;87:1235-1237.
  25. Muralikrishnan R, Venkatesh, R, Manohar Babu, B, Prajna NV. A Comparison of the Effectiveness and Cost-Effectiveness of Three Different Methods of Cataract Extraction in Relation to the Magnitude of Postoperative Astigmatism. Asia Pacific J. 2003;5:5-12.
  26. Praveen, K Nirmalan, Lalitha, Prajna and Prajna NV. Can Antiseptic Scrubs between Cataract Surgeries Reduce Bacterial Load on Surgical Gloves to Safe Levels. Br J Ophthalmol. 2004;88:438-439.
  27. Venkatesh R, Muralikrishnan, R, Eong, Kah-Guan Au, Saw, Seang-Mei, Aravind, S, Jacob Mathew, Kim, R, Prajna NV. Visual Experience during Phacoemulsification under Topical versus Retrobulbar Anesthesia: results of a prospective, randomized, controlled trial. Am. J. Ophthalmol. 2004;138:782-787.
  28. Prajna NV, Praveen, K Nirmalan, Mahalakshmi, Rajendran, Lalitha, Prajna, Srinivasan, M.Concurrent Use of 5 Percentage Natamycin and 2 Percentage Econazole for the Management of Fungal Keratitis. Cornea. 2004;23:793-796.
  29. Srinivasan, M, Sangita Prasad, Prajna NV. Late Dislocation of LASIK Flap following Fingernail Injury. Indian J Ophthalmol. 2004;52:327-328
  30. Muralikrishnan R, Venkatesh, R, Prajna NV, Frick, Kevin D. Economic Cost of Cataract Surgery Procedures in an Established Eye Care Centre in Southern India. Ophthalmic Epidemiol. 004;11:369-380.
  31. Srinivasan, M, Lalitha, Prajna and Prajna NV. A Cluster of Cases of Mycobacterium Chelonei Keratitis following Penetrating Keratoplasty. Indian J Ophthalmol. 2005;53:67-68.
  32. Haripriya Aravind, Lalitha, Prajna, Minu, M Mathen, Prajna NV, Kim, R, Shukla, Dhananjay, Natchiar, G, Srinivasan, M. Nocardia Endophthalmitis after Cataract Surgery: clinicomicrobiological study. Am. J. Ophthalmol. 2005;139:837-846.
  33. Venkatesh R, Muralikrishnan, R, Balent, Linda Civerchia, Prakash, Karthik, Prajna NV.Outcomes of High Volume Cataract Surgeries in a Developing Country. Br J
    Ophthalmol. 2005;89:1079-1082.
  34.  Smitha S, Lalitha, Prajna, Prajna NV, Srinivasan, M. Susceptibility Trends of Pseudomonas Species from Corneal Ulcers. Indian J Med Microbiol. 2005;23:168-171.
  35. Lalitha, Prajna, Jyothsna, Rajagopalan, Karthik Prakash, Kim, R, Prajna NV, Srinivasan, M. Postcataract Endophthalmitis in South India: incidence and
    outcome. Ophthalmology. 2005;112:1885-1890.
  36.  Arpitha P, Prajna NV, Srinivasan, M, Muthukkaruppan, V R. High Expression of p63 Combined with a Large N,C Ratio Defines a Subset of Human Limbal Epithelial Cells: implications on epithelial stem cells. Invest. Ophthalmol. Vis. Sci. 2005;46:3631-3636.
  37.  Lalitha, Prajna, Srinivasan, M, Prajna NV. Rhodococcus Ruber as a Cause of Keratitis. Cornea. 2006;25:238-239.
  38.  Amit Kabra, Lalitha, Prajna, Kannan Mahadevan, Prajna NV, Srinivasan, M.Herpes Simplex Keratitis and Visual Impairment: a case series. Indian J Ophthalmol. 2006;54:23-27.
  39. Lalitha, Prajna, Prajna NV, Amit Kabra, Kannan Mahadevan, Srinivasan, M.Risk Factors for Treatment Outcome in Fungal Keratitis. Ophthalmology. 2006;113:526-530.
  40.  Gritz DC, Srinivasan, M, Smith, Scott D, Usha, Kim R, Lietman, Thomas M, Wilkins, John H, Priyadarshini, Brinda, Aravind, Srinivasan, Prajna NV, Smolin, Gilbert, Thulasiraj, R D, Selvaraj, Sivasubramaniam, Whitcher, John P. Antioxidants in Prevention of Cataracts in South India: methodology and baseline data. Ophthalmic Epidemiol. 2006;13:97-107.
  41. Gritz DC, Srinivasan, M, Smith, S D, Usha, Kim R, Lietman, T M, Wilkins, J H, Priyadharshini, B, John, R K, Aravind, S, Prajna NV, Thulasiraj, R D, Whitcher, J P. The Antioxidants in Prevention of Cataract Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol. 2006;90:847-851.
  42.  Vasanthi Mani, Prajna NV, Lalitha, Prajna, Kannan Mahadevan, Muthukkaruppan, V R.A Pilot Study on the Infiltrating Cells and Cytokine Levels in the Tear of Fungal Keratitis Patients. Indian J Ophthalmol. 2007;55:27-31.
  43. Prajna NV, Praveen, K Nirmalan, Saravanan, S, Srinivasan, M. Economic Analysis of Corneal Ulcers in South India. Cornea. 2007;26:119-122.
  44. Rohini G, Murugeswari, P, Prajna NV, Lalitha, Prajna, Muthukkaruppan, V R. Matrix Metalloproteinases (MMP-8, MMP-9) and the Tissue Inhibitors of Metalloproteinases (TIMP-1, TIMP-2) in Patients With Fungal Keratitis. Cornea. 2007;26:207-211.
  45. Lalitha Prajna, Mamta Tiwari, Prajna NV, Gilpin, Christopher, Karthik Prakash, Srinivasan, M. Nocardia Keratitis: species, drug sensitivities, and clinical correlation. Cornea. 2007;26:255-259.
  46. Lalitha Prajna, Shapiro, Brett L, Srinivasan, M, Prajna NV, Acharya, Nisha R, Fothergill, Annette W, Ruiz, Jazmin, Chidambaram, Jaya D, Maxey, Kathryn J, Hong, Kevin C, McLeod, Stephen D, Lietman, Thomas M.Antimicrobial Susceptibility of Fusarium, Aspergillus, and other Filamentous Fungi Isolated from Keratitis. Arch Ophthal. 2007;125:789-793.
  47. Revathy R, Lalitha, Prajna, Anita Raghavan, Manikandan, P, Namperumalsamy, P, Prajna NV.Traumatic Lenticular Abscess: Clinical Description and outcome. Am. J. Ophthalmol. 2007;144:144-146.
  48. Arpitha Parthasarathy, Prajna NV, Srinivasan, M, Muthukkaruppan, V R.A Method to Isolate Human Limbal cells Enriched for a Subset of Epithelial Cells with a large Nucles/ Cytoplasm ratio Expressing High Levels of p63. Microsc Res Tech. 2008;71:469-476.
  49. Ananthi S, Chitra Thangavel, Bini, Ramachandran, Prajna NV, Lalitha, Prajna, Dharmalingam, K.Comparative analysis of the tear Protein Profile in Mycotic Kertitis Patients. Mol. Vis. 2008;9:500-507.
  50. Hemadevi B, Veitia, R A, Srinivasan, M, Arun Kumar, Jambulingam, Prajna NV, Lesaffre, C, Sundaresan, P. Identification of Mutations in the SLC4A11 Gene in Pateients with Recessive Congenital Hereditary Endothelial Dystrophy. Arch Ophthal. 2008;126:700-708.
  51. Lalitha Prajna, Vijaykumar, R, Prajna NV, Fothergill, A W. In Vitro Natamycin Susceptibility of Ocular Isolates of Fusarium and Aspergillus Species: comaprision of commercially formulated Natamycin Eye drops to pharmaceutical grade Powder. J. Clin. Microbiol. 2008;46:3477-3478.
  52. Arpitha Parthasarathy, Prajna NV, Srinivasan, M, Muthukkaruppan, V R.A Subset of Human Limbal Epithelial Cells with Greater Nucleus-to-Cytoplasm Ratio Expressing High Levels of p63 Possesses Slow-Cycling Property. Cornea. 2008;27:1164-1170.
  53. Srinivasan M, Lalitha, Prajna, Mahalakshmi, Rajendran, Prajna NV, Jeena Mascarenhas, Chidambaram, J D, Lee, S, Hong, K C, Zegans, M E, Glidden, D V, McLeod, S, Whitcher, J P, Lietman, T M, Acharya, N R. Corticosteroids for Bacterial Corneal Ulcers. Br J Ophthalmol. 2009;93:198-202.
  54. Day S, Lalitha, Prajna, Haug, S, Fothergill, A W, Cevallos, G, Vijayakumar, R, Prajna NV, Acharya, N R, McLead, S D, Lietman, T M.Activity of Antibiotics against Fusarium and Aspergillus. Br J Ophthalmol. 2009;93:116-119.
  55. Henderson BA, Kim, J Y, Golnik, K C, Oetting, T A, Lee, A G, Volpe, N J, Aaron, M, Uhler, T A, Arnold, A, Dunn, J P, Prajna NV, Lane, A M, Loewenstein, JI.Evaluation of the Virtual Mentor Cataract Training Program. Ophthalmology. 2010;117:253-258.
  56. Shapiro Brett L, Lalitha, Prajna, Loh, Allison R, Fothergill, Annette W, Prajna NV, Srinivasan, M, Kabra, Amit, Chidambaram, Jaya, Acharya, Nisha R, Lietman, Thomas M. Susceptibility Testing and Clinical Outcome in Fungal Keratitis. Br J Ophthalmol. 2010;94:384-385.
  57. Prajna NV, Jeena, Mascarenhas, Thiruvengada Krishnan, Ravindranath Reddy, P, Lalitha, Prajna, Srinivasan, M, Vaitilingam, C M, Hong, Kevin C, Lee, Salena M, McLeod, Stephen D, Zegans, Michael E, Porco, Travis C, Lietman, Thomas M, Acharya, Nisha R. Comparison of Natamycin and Voriconazole for the Treatment of Fugnal Keratitis. Arch Ophthal. 2010;128:672-678.
  58. Mehta Jodhbir Singh, Hemadevi, Boomiraj, Vithana, Eranga N, Arun Kumar, Jambulingam, Srinivasan, M, Prajna NV, Tan, Donald T, Aung, Tin, Sundaresan, P. Absence of Phenotype-Genotype Correlation of Patients Expressing Mutations in the SLC4A11 Gene. Cornea. 2010;29:302-306.
  59. Hemadevi B, Srinivasan, M, Arun Kumar, Jambulingam, Prajna NV, Sundaresan, P.Genetic Analysis of Patients with Fuchs Endothelial Corneal Dystrophy in India. BMC Ophthalmol. 2010;10.
  60. Senthilkumari S, Lalitha, Prajna, Prajna NV, Haripriya, Aravind, Nirmal, J, Gupta, P, Velpandian, T. Single and multidose Ocular Kinectics and Stability Analysis of Extemporaneous Formulation of Topical Voriconazole in Humans. Curr Eye Res. 2010;35:953-960.
  61. Ananthi S, Santhosh, R S, Valar Nila, M, Prajna NV, Lalitha, Prajna, Dharmalingmam, K. Comparative Proteomics of Human Male and Female Tears by Two-Dimensional Electrophoresis. Exp Eye Res. 2011;92:454-463.
  62. Lalitha Prajna, Shaprio, Brett L, Loh, Allison R, Fothergill, Annette W, Prajna NV,
    Srinivasan, M, Oldenburg, Catherine E, Quigley, David A, Chidambaram, Jaya D, McLeod, Stephen D, Acharya, Nisha R, Lietman, Thomas M.Amphotericin B and Natamycin are not Synergistic In Vitro against Fusarium and Aspergillus spp. Isolated from Keratitis. Br J Ophthalmol. 2011;95:744-745.
  63. Oldenburg CE, Prajna NV, Lalitha, Prajna, Thiruvengada Krishnan, Jeena Mascarenhas, Vaitilingam, C M, Srinivasan, M, See, Craig W, Cevallos, Vicky, Zegans, Michael E, Acharya, Nisha R, Lietman, Thomas M. Clinical Signs in Dematiaceous and Hyaline Fungal Keratitis. Br J Ophthalmol. 2011;95:750-751.
  64. Karthikeyan RS, Leal Jr., S M, Prajna NV, Dharmalingam, K, Geiser, D M, Pearlman, E, Lalitha, Prajna. Expression of Innate and Adaptive Immune Mediatros in Human Corneal Tissue Infected with Aspergillus or Fusarium. J Infect Dis. 2011;204:942-950.
  65. Gowri Priya C, Arpitha, Parthasarathy, Vaishali, S, Prajna NV, Usha, Kim R, Sheetal, K, Muthukkaruppan, V R. Adult Human Buccal Epithelial Stem Cells: identification, ex-vivo expansion, and transplantation for corneal surface reconstruction. Eye. 2011;25:1641-1649.
  66. Thiruvengada Krishnan, Prajna NV, Gronert, K, Oldenburg CE, Ray, K J, Keenan, JD, Lietman, T M, Acharya, N R. Gender Differences in Re-Epithelialisation Time in
    Fungal Corneal Ulcers. Br J Ophthalmol.  2012;96:137-8.
  67. Lalitha Prajna, Prajna NV, Oldenburg CE, Srinivasan, M, Thiruvengada Krishnan, Jeena Mascarenhas, Vaitilingam, C M, McLeod, S D, Zegans, M E, Porco, T C, Acharya, Nisha R, Lietman, T M. Organism, Minimum Inhibitory Concentration, and Outcome in a Fungal Corneal Ulcer Clinical Trial. Cornea. 2012;31:662-667.
  68. Lalitha Prajna, Lin, C C, Srinivasan, M, Jeena Mascarenhas, Prajna NV, Keenan, J D, McLeod, S D, Acharya, Nisha R, Lietman, T M, Porco, T C. Acanthamoeba Keratitis in South India: a longitudinal analysis of epidemics. Ophthalmic Epidemiol. 2012 ;19:111-5.
  69. Dalmon CP, Travis C, Lietman, Thomas M, Prajna NV, Lalitha, Prajna, Mano Ranjan Das, Arun Kumar, J, Jeena Mascarenhas, Margolis, Todd P, Whitcher, John P, Jeng, Bennie H, Keenan, Jeremy D, Chan, Matilda F, McLeod, Stephen D,Acharya, Nisha R. The Clinical Differentiation of Bacterial and Fungal Keratitis: a photographic survey. Invest. Ophthalmol. Vis. Sci. 2012;53:1787-91.
  70. Manoharan G, Lalitha, Prajna, Jeganathan, L P, Dsilva, S S, Prajna NV. Pantoea Ananatis as a cause of Corneal Infiltrate after Rice Husk Injury – A Case Report. J. Clin. Microbiol. 2012;50:2163-4.
  71. Prajna NV, Thiruvengada Krishnan, Jeena Mascarenhas, Srinivasan, M, Oldenburg, C E, Toutain-Kidd, C M, Sy, A, McLeod, S D, Zegans, M E, Acharya, N R, Lietman, T M, Porco, T C. Predictors of Outcome in Fungal Keratitis. Eye. 2012;26:1226-1231.
  72. Lin CC, Lalitha, Prajna, Srinivasan, M, Prajna NV, McLeod, Stephen D, Acharya, Nisha R, Lietman, Thomas M, Porco, Travis C. Seasonal Trends of Microbial Keratitis in South India. Cornea .2012;31:1123-1127.
  73. Prajna NV, Lalitha, Prajna, Jeena Mascarenhas, Thiruvengada Krishnan, Srinivasan, M, Vaitilingam, C M, Oldenburg, Catherine E, Sy, Aileen, Keenan, Jeremy David, Porco, Travis C, Acharya, Nisha R, Lietman, Thomas M. Natamycin and Voriconazole in Fusarium and Aspergillus Keratitis: subgroup analysis of a randomised controlled trial. Br J Ophthalmol. 2012;96:1440-1441.
  74. Gowri Priya C, Tilak Prasad, Prajna NV, Muthukkaruppan, V R. Identification of Human Corneal Epithelial Stem Cells on the Basis of High ABCG2 Expression Combined with a Large N/C Ratio. Microsc Res Tech. 2013;76:242-8.
  75. Prajna NV, Thiruvengada Krishnan, Jeena Mascarenhas, Revathy, R, Lalitha, Prajna, Srinivasan, M, Anita Raghavan, Oldenburg, Catherine E, Ray, Kathryn J, Zegans, Michael E, McLeod, Stephen D, Porco, Travis C, Acharya, Nisha R, Lietman, Thomas M, Mycotic Ulcer Treatment Trial Group. The Mycotic Ulcer Treatment Trial: a randomized trial comparing natamycin vs voriconazole. JAMA Ophthalmol. 2013;131:422-429.
  76. Ananthi S, Prajna NV, Lalitha, Prajna, Valar Nila, M, Dharmalingam, K. Pathogen Induced Changes in the Protein Profile of Human Tears from Fusarium Keratitis Patients. PLOS One. 2013;8:1-16
  77. Anshuman Verma, Mano Ranjan Das, Srinivasan, M, Prajna NV, Sundaresan, P. Investigation of VSX1 Sequence Variants in South Indian Patients with Sporadic Cases of Keratoconus. BMC Res Notes. 2013;6:103.
  78. Prajna NV, Srinivasan, M, Lalitha, Prajna, Thiruvengada Krishnan, Revathy, R, Meenakshi, R, Jeena Mascarenhas, Oldenburg, C E, Ray, K J, McLeod, S D, Acharya, N R, Lietman, T M. Differences in Clinical Outcomes in Keratitis Due to Fungus and Bacteria. JAMA Ophthalmol. 2013;131:1088-1089.
  79. Sun CQ, Prajna NV, Thiruvengada Krishnan, Jeena Mascarenhas, Revathy, R, Srinivasan, M, Anita Raghavan, O'Brien, K S, Ray, K J, McLeod, S D, Porco, T C, Acharya, N R, Lietman, T M. Expert Prior Elicitation and Bayesian Analysis of the Mycotic Ulcer Treatment Trial I. Invest. Ophthalmol. Vis. Sci. 2013;54:4167-4173.
  80. Jeena Mascarenhas, Lalitha, Prajna, Prajna NV, Srinivasan, M, Mano Ranjan Das, Sean, S D'Silva, Oldenburg, C E, Borkar, D S, Esterberg, E J, Lietman, T M,
    Keenan, J D. Acanthamoeba, Fungal, and Bacterial Keratitis: a comparison of risk factors and clinical features. Am. J. Ophthalmol. 2014 Jan;157(1):56-62.
  81. Lalitha Prajna, Sun, Catherine Q, Prajna NV, Karpagam, R, Geetha, M, O'Brien, Kieran S, Cevallos, Vicky, McLeod, Stephen D, Acharya, Nisha R, Lietman, Thomas M, Mycotic Ulcer Treatment Trial Group. In Vitro Susceptibility of Filamentous Fungal Isolates from a Corneal Ulcer Clinical Trial. Am. J. Ophthalmol. 2014;157:318-326.
  82. Toutain-Kidd CM, Proco, Travis C, Kidd, Eric M, Srinivasan, M, Prajna NV, Acharya, Nisha, Lietman, Thomas, Zegans, Michael E. Evaluation of Fungal Keratitis using a Newly Developed Computer Program, Optscore, for Grading Digital Corneal Photographs. Ophthalmic Epidemiol. 2014;21:24-32.
  83. McClintic SM, Prajna NV, Srinivasan, M, Jeena Mascarenhas, Lalitha, Prajna, Revathy, R, Oldenburg, C E, O'Brien, K S, Ray, K J, Acharya, N R, Lietman, T M, Keenan, J D. Visual Outcomes in Treated Bacterial Keratitis: four years of prospective follow-up. Invest. Ophthalmol. Vis. Sci..2014;55:2935-2940
  84. Sun CQ, Lalitha, Prajna, Prajna NV, Karpagam, R, Geetha, M, O'Brien, K S, Oldenburg, C E, Ray, K J, McLeod, S D, Acharya, N R, Lietman, T M, Mycotic
    Ulcer Treatment Trial Group.Association between In Vitro Susceptibility to Natamycin and Voriconazole and Clinical Outcome in Fungal Keratitis. Ophthalmology. 2014;121:1495-1500.
  85. Karthikeyan RS, Vareechon, C, Prajna NV, Dharmalingam, K, Pearlman, E, Lalitha, P. IL-17 Expression in Peripheral Blood Neutrophils from Fungal Keratitis Patients and Healthy Cohorts in South India. J Infect Dis. 2015;211:130-4.
  86. Muthu Selvam, R Nithya, R, Devi, P N, Shree, R S, Valar Nila, M, Demonte, N L, Thangavel, C, Jeya Maheshwari, J, Lalitha, P, Prajna NV, Dharmalingam, K.Exoproteome of Aspergillus Flavus Corneal Isolates and Saprophytes: identification of proteoforms of an oversecreted alkaline protease. J Proteomics. 2014;115C:23-35.
  87. Revathy R, Parameshwar, B, Vikram, V, Sowmyalatha, M, Anita Raghavan, Siddharthan, S, Prajna NV. Topical 5 Percentage Natamycin with Oral Ketoconazole in Filamentous Fungal Keratitis: a randomized controlled trial. Asia Pac J Ophthalmol. 2015;4:146-50.
  88. Lalitha Prajna, Prajna NV, Geetha, M, Srinivasan, M, Jeena Mascarenhas, Mano Ranjan Das, D'Silva, S S, Porco, T C, Keenan, J D. Trends in Bacterial and Fungal Keratitis in South India, 2002-2012. Br J Ophthalmol. 2015;99:192-4.
  89. Madhu Uddaraju, Jeena Mascarenhas, Mano Ranjan Das, Prajna NV. A Case of Bilateral, Multiple Symmetric Concentric ring-Shped Opacities in the Cornea. JAMA Ophthalmol. 2015;133:483-484.
  90. Saumi Mathews, Chidambaram, J D, Lanjewar, S, Jeena Mascarenhas, Prajna NV, Muthukkaruppan, V R, Gowri Priya, C. In Vivo Confocal Microscopic Analysis of Normal Human Anterior Limbal Stroma. Cornea. 2015;34:464-470.
  91. Rose-Nussbaumer J, Prajna NV, Thiruvengada Krishnan, Jeena Mascarenhas, Revathy, R, Srinivasan, M, Anita Raghavan, Oldenburg, C E, O'Brien, K S, Ray, K J, McLeod, S D, Porco, T C, Lietman, T M, Acharya, N R, Keenan, J D, Mycotic Ulcer Treatment Trial I Group. Vision-Related Quality-of-Life Outcomes in the Mycotic Ulcer Treatment Trial I: a randomized clinical trial. JAMA Ophthalmol. 2015;133:642-646.
  92. Madhu Uddaraju, Jeena Mascarenhas, Mano Ranjan Das, Naveen, R, Keenan, JD, Lalitha, Prajna, Prajna NV. Corneal Cross-Linking as an Adjuvant Therapy in the Management of Recalcitrant Deep Stromal Fungal Keratitis: a randomized trial. Am. J. Ophthalmol. 2015;160:131-134.
  93. Sayali Pradhan, Mano Ranjan Das, Panigrahi, A K, Prajna NV. Severe Conjunctival Reaction following Attempted Corneal Tattooing. JAMA Ophthalmol. 2015;133:854-856.
  94.  Prajna NV, Lalitha, Prajna, O'Brien, K S, Sun, C Q, Acharya, N, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. Association of Pretreatment with Antifungal Medication and Fungal Resistance in the Mycotic Ulcer Treatment Trial. JAMA Ophthalmol. 2015;133:1210-1211.
  95. Muthu Selvam R, Nithya, R, Narmatha Devi, P, Bhuvana Shree, R S, Valar Nila, M, Demonte, N L, Thangavel, C, Jeya Maheshwari, J, Lalitha, Prajna, Prajna NV, Dharmalingam, K. Data Set for the Mass Spectrometry Based Exoproteome Analysis of Aspergillus Flavus Isolates. Data Brief. 2015;2:42-47.
  96. Gowri Priya C, Saumi Mathews, Arun Kumar, P, Jeena Mascarenhas, Prajna NV, Muthukkaruppan, V R. In Vivo Confocal Microscopic Analysis of Limbal Stroma in Patients with Limbal Stem Cell Deficiency. Cornea. 2015;34:1478-1486.
  97. Rose-Nussbaumer ,J Prajna NV, Thiruvengada Krishnan, Jeena Mascarenhas, Revathy, R, Srinivasan, M, Anita Raghavan, Oldenburg, C E, O'Brien, K S, Ray, K J, Porco, T C, McLeod, S D, Acharya, N R, Keenan, J D, Lietman, T M, Mycotic Ulcer Treatment Trial Group. Risk Factors for Low Vision Related Functioning in the Mycotic Ulcer Treatment Trial: a randomised trial comparing natamycin with voriconazole. Br J Ophthalmol. 2016;100:929-932.
  98. Prajna NV, Lalitha, Prajna, Revathy, R, Thiruvengada Krishnan, Anita Raghavan, Srinivasan, M, O'Brien, Kieran S, Zegans, Michael, McLeod, Stephen D, Acharya, Nisha R, Keenan, Jeremy D, Lietman, Thomas M, Rose-Nussbaumer, Jennifer, Mycotic Ulcer Treatment Trial Group.Changing Azole Resistance: a secondary analysis of the MUTT I randomized clinical trial. JAMA Ophthalmol. 2016;134:693-696.
  99. Lokeshwari A, Naveen, R, Prajna NV, Lalitha, Prajna. Clinical and Microbiological Study of Paediatric Infectious Keratitis in South India: a 3-year study (2011-2013). Br J Ophthalmol. 2016;100:1719-1723.
  100. Prajna NV, Lumbini Devi, Suganya, K S, Keenan, J D. Conjunctival Autograft versus Amniotic Membrane Transplantation after Double Pterygium Excision: a randomized trial. Cornea. 2016;35:823-826.
  101.  Soham Basak, Prajna NV .A Prospective, In Vitro, Randomized Study to
    Compare Two Media for Donor Corneal Storage. Cornea. 2016;35:1151-1155.
  102. Sun CQ, Prajna NV, Thiruvengada Krishnan, Revathy, R, Srinivasan, M, Anita Raghavan, O'Brien, K S, McLeod, S D, Acharya, N R, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. Effect of Pretreatment with Antifungal Agents on Clinical Outcomes in Fungal Keratitis. Clin Experiment Ophthalmol. 2016;44:763-767.
  103. Soundaram M, Aalia Rasool Sufi, Prajna NV, Keenan, Jeremy D. Comparison of In Vivo Confocal Microscopy, Ultrasonic Pachymetry, and Scheimpflug Topography for Measuring Central Corneal Thickness. JAMA Ophthalmol. 2016;134:1057-1059.
  104. Dangra KL, Mano Ranjan Das, Sundaresan, P, Prajna NV. Bilateral Atypical Granular Corneal Dystrophy Associated with Unilateral Keratoconus in a Male Child. Middle East Afr J Ophthalmol. 2016;23:262-264.
  105. Chidambaram JD, Prajna NV, Larke, N L, Srikanthi, P, Shruti, L, Manisha Shah, Elakkiya, S, Lalitha, Prajna, Carnt, N, Vesaluoma, M H, Mason, M, Hau, S, Burton, M J. Prospective Study of the Diagnostic Accuracy of the In Vivo Laser Scanning Confocal Microscope for Severe Microbial Keratitis. Ophthalmology. 2016;123:2285-2293.
  106. Prajna NV, Thiruvengada Krishnan, Revathy, R, Patel, S, Srinivasan, M, Mano Ranjan Das, Ray, K J, O'Brien, K S, Oldenburg, C E, McLeod, S D, Zegans, M E, Porco, T C, Acharya, N R, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatmetn Trial II Group. Effect of Oral Voriconazole on Fungal Keratitis in the Mycotic Ulcer Treatment Trial II (MUTT II): a randomized clinical trial. JAMA Ophthalmol. 2016;134:1365-1372.
  107. Jeyalakshmi K, Demonte, N L, Prajna NV, Lalitha, Prajna, Chitra, T, Jeya Maheshwari, J, Dharmalingam, K. Aspergillus Flavus Induced Alterations in Tear Protein Profile Reveal Pathogen-Induced Host Response to Fungal Infection. J Proteomics. 2016;152.
  108. Jhansi Rani K, Prajna NV, Muthukkaruppan, V R, Gowri Priya, C. A Novel Method for a High Enrichment of Human Corneal Epithelial Stem Cells for Genomic Analysis. Microsc Res Tech. 2016;79:1165-1172.
  109. Jeyalakshmi K. Data Set of Aspergillus Flavus Induced Alterations in Tear Proteome: understanding the pathogen-induced host reponse to fungal infection. Data Brief. 2016;9:888-894.
  110. Lalitha Prajna, Geetha, M, Karpagam, R, Prajna NV, Srinivasan, M, Jeena Mascarenhas, Mano Ranjan Das, Porco, T C, Lietman, T M, Cevallos, V, Keenan, J D. Trends in Antibiotic Resistance in Bacterial Keratitis Isolates from South India. Br J Ophthalmol. 2017;101:108-113.
  111. Chidambaram JD, Prajna NV, Larke, N, Macleod, D, Srikanthi, P, Shruti, L, Manisha Shah, Lalitha, Prajna, Elakkiya, P, Burton, M J. In Vivo Confocal Microscopy Appearance of Fusarium an Aspergillus Species in Fungal Keratitis. Br J Ophthalmol. 2017;101:1119-1123.
  112. Rohan A, Naveen, R, Sayali Pradhan, Srinivasan, M, Prajna NV, Lalitha, Prajna. Clinical and Demographic Study of Microsporidial Keratoconjunctivitis in South India: a 3-year study (2013-2015). Br J Ophthalmol. 2017;101:1436-1439.
  113. Madhavi Latha Y, Bhagyashree, M, Nilam, Gohil, Hitha Sara, S, Prajna NV, Senthilkumari, S. In Vitro Evaluation of the Drug Reservoir Function of Human Amniotic Membrane using Moxifloxacin as a Model Drug. Cornea. 2017;36:594-599.
  114. Ray KJ, Lalitha, Prajna, Prajna NV, Revathy, R, Thiruvengada Krishnan, Srinivasan, M, Ryg, R, McLeod, S, Acharya, N R, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial. The Utility of Repeat Culture inFungal Corneal Ulcer Management: a secondary analysis of the MUTT I randomized clinical trial group. Am. J. Ophthalmol. 2017;178:157-162.
  115.  Prajna NV, Thiruvengada Krishnan, Revathy, R, Patel, S, Shah, R, Srinivasan, M, Lumbini Devi, Mano Ranjan Das, Ray, K J, O'Brien, K S, Oldenburg, C E, McLeod, S D, Zegans, M E, Acharya, N R, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. Adjunctive Oral Voriconazole Treatment of Fusarium Keratitis: a secondary analysis from the mycotic ulcer treatment trial II. JAMA Ophthalmol. 2017;135:520-525.
  116. Chidambaram JD, Kannambath, S, Srikanthi, P, Manisha Shah, Lalitha, Prajna, Elakkiya, S, Bauer, J, Prajna NV, Holland, M J, Burton, M J.Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: results from a comparative transcriptome analysis. Front Cell Infect Microbiol. 2017;7:193.
  117. Hemadevi B, Prajna NV. Genetic Perspective of Corneal Endothelial Dystrophies. JSM Genet Genomics. 2017;4:1026.
  118. Prajna NV, Thiruvengada Krishnan, Revathy, R, Patel, S, Shah, R, Srinivasan, M, Mano Ranjan Das, Ray, K J, Oldenburg, C E, McLeod, S D, Zegans, M E, Acharya, N R, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. Predictors of Corneal Perforation or Need for Therapeutic Keratoplasty in Severe Fungal Keratitis: a secondary analysis of the mycotic ulcer treatment trial II. JAMA Ophthalmol. 2017;135:987-991.
  119. Arun Kumar P, Lokeshwari, A, Pajna NV. Argyrosis. Ophthalmology. 2017;124:1270.
  120.  Lumbini Devi, Prajna NV Prajna NV, Srinivasan, M, Naveen, R, Mano Ranjan Das.Microsporidial Infection Masquerading as Graft Rejection Post-Descemet's Stripping Automated Endothelial Keratoplasty. Indian J Ophthalmol. 2017;65:869-870.
  121. Prajna NV, Lalitha, Prajna, Srinivasan, M. Fungal Keratitis: the Aravind experience. Indian J Ophthalmol. 2017;65:912-919.
  122.  Oldenburg CE, Prajna NV, Amza, A, Loh, A, Acharya, N R, Mannis, M J, Lietman, T M.Evolution of Practice Patterns for the Treatment of Fungal Keratitis. JAMA Ophthalmol. 2017;135:1448-1449.
  123.  Durga M, Prajna NV, Lumbini Devi, Sundaresan, P. Genetic Analysis of CHST6 Gene in Indian Families with Macular Corneal Dystrophy. Int J Gen Sci. 2017;4:1-10.
  124. Patel TP, Prajna NV, Farsiu, S, Valikodath, N G, Niziol, L M, Lakshey, D, Kim, K H, Woodward, M A. Novel Image-Based Analysis for Reduction of Clinician-Dependent Variability in Measurment of the Corneal Ulcer Size. Cornea. 2018;37:331-339.
  125. Hemalatha G, Uddaraju, Madhu, Sayali, Pradhan, Mano Ranjan Das, Jeena, Mascarenhas, Srinivasan, M, Prajna NV. Ocular Manifestations of Isolated Corneal Bee Sting Injury, Management Strategies, and Clinical Outcomes. Indian J Ophthalmol. 2018;66:262-268.
  126. Ray KJ, Prajna NV, Lalitha, Prajna, Revathy, R, Thiruvengada Krishnan, Patel, S, Mano Ranjan Das, Shah, R, Dhakhwa, K, McLeod, S D, Zegans, M E, Acharya, N R, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. The Significance of Repeat Cultures in the Treatment of Severe Fungal Keratitis. Am. J. Ophthalmol. 2018;189:41-46.
  127. Prajna NV, Manisha Shah. Good Quality Pays Rich Dividends. Indian J Ophthalmol. 2018;66:357-358.
  128. Chidambaram JD, Prajna NV, Srikanthi, P, Shruti, L, Manisha Shah, Elakkiya, S, Macleod, D, Lalitha, P, Burton, M J. In Vivo Confocal Microscopy Cellular Features of Host and Organism in Bacterial, Fungal and Acanthamoeba Keratitis. Am. J. Ophthalmol. 2018;190:24-33.
  129. Chidambaram JD, Prajna NV, Srikanthi, P, Shruti, L, Manisha Shah, Elakkiya, S, Lalitha, Prajna, Burton, M J.Epidemiology, Risk Factors, and Clinical Outcomes in Severe Microbial Keratitis in South India. Ophthalmic Epidemiol. 2018;25:297-305.
  130. Oldenburg CE, Prajna NV, Thiruvengada Krishnan, Revathy, R, Srinivasan, M, Ray, K J, O'Brien, K S, Glymour, M M, Porco, T C, Acharya, N R, Rose-Nussbaumer, J, Lietman, T M. Regression Discontinuity and Randomized Controlled Trial Estimates: an application to the mycotic ulcer treatment trials. Ophthalmic Epidemiol. 2018;25:315-322.
  131. Lakshey D, Lakshmi Priya, J, Prajna NV, Lalitha, Prajna. Fungal Keratitis caused by Laetisaria Arvalis. Indian J Med Microbiol. 2018;36:140-142.
  132. Cho J, Prajna NV, Lalitha, Prajna, Revathy, R, Thiruvengada Krishnan, Lin, Y B, Ray, K J, Lietman, T M, Rose-Nussbaumer, J, Mycotic Ulcer Treatment Trial Group. Therapeutic Penetrating Keratoplasty Button Culture in the Mycotic Ulcer Treatment Trial II: a randomized trial comparing oral voriconazole vs placebo. Am. J. Ophthalmol. 2018 Epub.
  133. Prajna NV. Take Time to Sharpen the Saw. Indian J Ophthalmol. 2018;66:784.
  • Distinction in Forensic Medicine on  1986
  • Dr. Mahendra Chandra Mishra Oration Award at the Orissa State Conference at Cuttack on  April 10 & 11, 1999
  • Amjad Rahi Best Paper Award at the 11th Annual Meeting of the Indian Eye Research Group (IERG) held at LVPEI, Hyderabad in January 19-20, 2002.
  • Capt Subramaniam gold medal award for the best video at the 58th Tamil Nadu Ophthalmic Association (TNOA) at Salem on July 30th & 31st, 2010.
  • Gold Medal for exemplary work in the field of ophthalmology at the Annual Conference of the Bombay Ophthalmologists’ Association (BOA) held at Mumbai in August 13th–15th, 2010.
  • Gold Medal for contribution to research and residency education at the Annual Conference of the IIRSI held at Chennai in July 5-6th, 2014.
  • Coauthor for the John Lee Best Poster award given by the Royal College of Ophthalmologists , London, 2015